See all Cafe in Ann Arbor Ann Arbor for: Adventure, Food And Dining, Art And Culture, Nightlife, Spa, History, First Timers, Family, Romance, Shopping Prickly Pear Southwest Cafe 328 S Main St Phone: ☎ +1 734 930-0047 About Prickly Pear Southwest Cafe, 328 S Main St, ☎ +1 734 930-0047. M 5PM-9PM, Tu-Th 11:30AM-9PM, F-Sa 11:30AM-10PM, Su 11:30AM-8:30PM. Southwestern food. Try the black bean rellenos and the empanadas. $10-$20. Add to Wish List
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