See all Zoo in Knoxville Knoxville for: Adventure, Food And Dining, Art And Culture, Nightlife, Spa, History, First Timers, Family, Romance, Shopping Knoxville Zoo 3500 Knoxville Zoo Drive About Knoxville Zoo, 3500 Knoxville Zoo Drive (Off 1-40 near Cherry Street), [27]. A nice but smallish zoo with 800 animals and a lot of success breeding red pandas. There's also a reptile center and kids play area. Add to Wish List