Kalayaan Avenue is a major east-west route in Makati, Metro Manila, Philippines. For most of its length, it runs parallel to J.P. Rizal Avenue to the north from East Rembo near Fort Bonifacio to Singkamas Village by the border with Santa Ana, Manila. It is interrupted by Bel-Air Village between Amapola Street and Epifanio de los Santos Avenue. The avenue is designated as a component of Radial Road 4 of the Metro Manila Arterial Road System.